![]() Hence, ECoG grids are a favorable modality for brain-computer interface applications, localization of epileptic foci for clinical epilepsy diagnosis and targeted tissue resection, and as a basic science tool. They have also been used to characterize cortical traveling waves, which have been shown to modulate perceptual sensitivity. Neurophysiological recordings with ECoG grids have been successfully used for speech synthesis, reproduction of arm movements, and spatial localization of ictal onset zones. ![]() Nonpenetrative, subdural ECoG grids laid on top of the brain surface are the gold standard for recording population-level activity, measured from the local field potential (LFP). Perception, thoughts, and actions involve the coordinated activity of large populations of neurons in multiple regions of the brain. ![]() This work could greatly increase the scalability of existing electrophysiological devices, potentially allowing them to capture cortex-wide activity in the brain such as thoughts, actions, and perception. ![]() Stanford Bio-X affiliated faculty members Nick Melosh and John Huguenard, with first author Stanford Bio-X Fellow Eric Zhao and co-author Travel Award recipient Pingyu Wang, have developed an electrode connector based on an ultra-conformable thin-film electrode array that self-assembles onto silicon microelectrode arrays, enabling multithousand channel counts at a millimeter scale. Photo of first author Eric Zhao, Stanford Bio-X Fellow and graduate student in the Melosh lab.
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